P-6: Effects of Green Biologic Rodenticide, Biorotox®, on Fertility of Male Rats

نویسندگان

  • A Tamadon Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz University, Shiraz, Iran
  • F Nowzari Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • F Rahmanifar Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
  • M Owjfard Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz University, Shiraz, Iran
  • MR Dorvash Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz University, Shiraz, Iran
چکیده مقاله:

Background Biorotox® is an invented green biologic rodenticide. The present study was designed to determine whether this toxin could cause infertility in male rats. MaterialsAndMethods Sixteen Sprague-Dawley adult male rats were randomly divided into control and treatment groups. Treatment group was received diets containing Biorotox ® for 35 days. Control group was given standard rat food. Weight of body and volume of testis were measured. Furthermore, epididymal semen samples were collected and incubated for 45 min at 37 °C in 1 mL of PBS, to evaluate sperm counts, motility and viability. Data of indices were evaluated using the independent sample t test. P0.05). Conclusion Biorotox® in the rat diet decreased motility of spermatozoa which may have an adverse effect on rat reproduction. And it could be an efficient product for control the population of these rodents.

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عنوان ژورنال

دوره 9  شماره 2

صفحات  46- 46

تاریخ انتشار 2015-09-01

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